Bristol-Myers Squibb Confirms Effectiveness and Safety of Sotyktu for the Treatment of Psoriatic Arthritis and Lupus with New Long-Term Data
Bristol-Myers Squibb Company (NYSE:BMY) is one of best NYSE stocks to buy and hold for the next decade. On October 27, Bristol Myers Squibb announced new data from week 52 of its pivotal phase 3 POETYK PsA-1 trial. These results further supported the efficacy and safety of Sotyktu (deucravacitinib) for the treatment of adults with active psoriatic arthritis/PsA who had not previously received a biologic disease-modifying antirheumatic drug/bDMARD.
The company also announced new results from an integrated analysis of the PAISLEY-SLE and PAISLEY Phase 2 long-term/LTE extension studies. Results showed durable safety and effectiveness with up to four years of treatment with Sotyktu for patients with moderate to severe systemic lupus erythematosus/SLE.
Sotyktu is an oral, selective tyrosine kinase 2/TYK2 inhibitor that represents a novel class of small molecules. It achieves its effect by selectively binding to the regulatory domain of TYK2, leading to allosteric inhibition of TYK2 and its downstream functions involving key cytokines. At therapeutic doses, Sotyktu does not inhibit JAK1, JAK2 or JAK3. The drug is already approved in many countries around the world for the treatment of adults with moderate to severe plaque psoriasis.
Bristol-Myers Squibb Company (NYSE: BMY) discovers, develops, licenses, manufactures, markets, distributes and sells biopharmaceutical products worldwide.
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Disclosure: None. This article was originally published on Initiated Monkey.
